SELECTED PUBLICATIONS

# Equal contribution

1. Laqtom NN. 2023. Studying lysosomal function and dysfunction using LysoIP. Nat Rev Mol Cell Biol. doi.org/10.1038/s41580-023-00619-6

2. Laqtom NN, Dong W, Medoh UN, Cangelosi AL, Dharamdasani V, Chan SH, Kunchok T, Lewis CA, Heinze I, Tang R, Grimm C, Do AND, Porter FD, Ori A, Sabatini DM, AbuRemaileh M. 2022.  CLN3 is required for the clearance of glycerophosphodiesters from lysosomes. Nature. 609, 1005–11. doi.10.1038/s41586-022-05221-y

3. Armenta D, Laqtom NN#, Alchemy G, Dong W, Morrow D, Alchemy G, Poltorack C, Nathanson D, Abu-Remalieh M, Dixon SJ. 2022. Ferroptosis inhibition by lysosomal protein catabolism. Cell Chem Biol. 24:S2451-9456(22)00360-9. doi: 10.1016/j.chembiol.2022.10.006.  

4. Pedram K, Laqtom NN, Shon DJ, Di Spiezio A, Riley NM, Saftig P, Abu-Remaileh M, Bertozzi, CR. 2022. Discovery of a pathway for endogenous mucin glycodomain catabolism in mammals. PNAS. 119(39):e2117105119.  

5. Vest RT, Chou C-C, Zhang H, Haney MS, Li L, Laqtom NN, Chang B, Shuken S, Nguyen A, Yerra L, Yang AC, Green C, Tanga M, Abu-Remaileh M, Bassik MC, Frydman J, Luo J, WyssCoray T. 2022. Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration. PNAS. 119 (11) e2121609119.

6. Rogala KB, Gu X, Kedir JF, Abu-Remaileh M, Bianchi LF, Bottino AMS, Dueholm R, Niehaus A, Overwijn D, Fils AP, Zhou SX, Leary D, Laqtom NN, Brignole EJ, Sabatini DM. 2019. Structural basis for the docking of mTORC1 on the lysosomal surface. Science. 366(6464): 468–475.

7. Abu-Remaileh M, Wyant GA, Kim C, Laqtom NN, Abbasi M, Chan SH, Freinkman E, Sabatini DM. 2017. Lysosomal metabolomics reveals v-ATPase and mTOR-dependent mechanisms for the efflux of amino acids from lysosomes. Science. 358(6364):807-813.